For generations, America’s competitive edge came from its ability to turn bold ideas into global influence. But today, the systems that fuel innovation are showing signs of strain. In this opening conversation, we’ll frame the central questions shaping this year’s Impact Council Annual Meeting: What does it take to sustain innovation in a moment of uncertainty? Where is America gaining—or losing—ground globally? And what responsibility do business leaders have in strengthening the ecosystems that drive economic growth and societal progress?